L Antigen Family Member 3 Serves as a Prognostic Biomarker for the Clinical Outcome and Immune Infiltration in Skin Cutaneous Melanoma

L Antigen Family Member 3 (LAGE3) is an important RNA modification-related protein. Whereas few studies have interrogated the LAGE3 protein, there limited data on its role in tumors. Here, we analyzed and profiled protein skin cutaneous melanoma (CM) using TCGA, GTEx, or GEO databases. Our showed upregulation of cell lines compared to normal lines. Besides, Kaplan–Meier curves Cox proportional hazard model revealed that was independent survival indicator for CM, especially metastatic CM. Moreover, negatively associated with multiple immune infiltration levels CD8+ T cells Taken together, our study suggests could be a potential prognostic biomarker might target development novel CM treatment strategies.